Subtract a pkproto object from a pk object | -.pk |
Add a `pkproto` object to a `pk` object | +.pk |
AAFE() | AAFE |
Default method for AAFE() | AAFE.default |
Calculate absolute average fold error (AAFE) | AAFE.pk |
Add various `pkproto` objects to a `pk` object | add_pk |
AFE() | AFE |
Default method for AFE() | AFE.default |
Calculate average fold error | AFE.pk |
Akaike information criterion | AIC.pk |
Analytic AUC for 1-compartment model | auc_1comp |
Analytic AUC for 1-compartment model with specific clearance | auc_1comp_cl |
Analytical AUC for the 2-compartment model | auc_2comp |
AUC for flat model | auc_flat |
Automatically select new time units | auto_units |
Bayesian information criterion | BIC.pk |
Calculate Hessian | calc_hessian |
Non-compartmental analysis | calc_nca |
Calculate RMSE (root mean squared error) | calc_rmse |
Calculate r-squared for observed vs. predicted values | calc_rsq |
Calculate parameter SDs | calc_sds_alerts |
Check methods | check_method |
Check models | check_model |
Check new data | check_newdata |
Check 1-compartment model parameters | check_params_1comp |
Check 1-compartment model parameters | check_params_1comp_cl |
Check 2-compartment model parameters | check_params_2comp |
Check flat model parameters | check_params_flat |
Check required status | check_required_status |
Default method for checking required status | check_required_status.default |
Check required status | check_required_status.pk |
Coefficient standard deviations | coef_sd |
Coefficient standard deviation default | coef_sd.default |
Get coefficient standard deviations | coef_sd.pk |
Get coefficients | coef.pk |
Combined standard deviation | combined_sd |
Model comparison | compare_models |
Default method for compare_models() | compare_models.default |
Model comparison for [pk()] objects | compare_models.pk |
Get concentration scalings | conc_scale_use |
Convert sample mean and SD to log10-scale | convert_summary_to_log10 |
Helper function to convert time units | convert_time |
Analytical 1-compartment model | cp_1comp |
Analytical 1-compartment model with specific clearance | cp_1comp_cl |
Analytical 2-compartment model | cp_2comp |
Time derivative of analytical 2-compartment model | cp_2comp_dt |
Flat model | cp_flat |
CvTdb data | cvt |
CvTdb download date | cvt_date |
data_summary() | data_summary |
Default method for data_summary() | data_summary.default |
Data summary for a `pk` object | data_summary.pk |
Log-normal distribution density function for summary data | dlnorm_summary |
Normal distribution density function for summary data | dnorm_summary |
do_data_info generic | do_data_info |
do_data_info default method | do_data_info.default |
calculate summary data info | do_data_info.pk |
Fitting | do_fit |
do_fit default method | do_fit.default |
Do fitting | do_fit.pk |
Prefitting | do_prefit |
do_prefit default method | do_prefit.default |
Do pre-fitting | do_prefit.pk |
Preprocess data generic | do_preprocess |
do_preprocess default method | do_preprocess.default |
Do pre-processing | do_preprocess.pk |
eval_tkstats() | eval_tkstats |
Default method for eval_tkstats() | eval_tkstats.default |
Evaluate TK statistics | eval_tkstats.pk |
Facet a PK fit | facet_data |
Fill parameters for 1-compartment model | fill_params_1comp |
Fill parameters for 1-compartment model with specific clearance | fill_params_1comp_cl |
Fill parameters for 2-compartment model | fill_params_2comp |
Fill parameters for flat model | fill_params_flat |
Fit a single group of data | fit_group |
Fold error | fold_error |
fold_error default method | fold_error.default |
Fold errors | fold_error.pk |
get_data() | get_data |
get_data_group() | get_data_group |
Default method for get_data_group() | get_data_group.default |
Get data grouping | get_data_group.pk |
get_data_info() | get_data_info |
Default method for get_data_info() | get_data_info.default |
Get data_info | get_data_info.pk |
get_data_original() | get_data_original |
Default method for get_data_original() | get_data_original.default |
Get data_original | get_data_original.pk |
get_data_sigma_group() | get_data_sigma_group |
Default method for get_data_sigma_group() | get_data_sigma_group.default |
Get data_sigma_group | get_data_sigma_group.pk |
get_data_summary() | get_data_summary |
Default method for get_data_summary() | get_data_summary.default |
Default method for get_data() | get_data.default |
Get data | get_data.pk |
Get an elbow point | get_elbow |
get_error_group() | get_error_group |
Default method for get_error_group() | get_error_group.default |
Get error group | get_error_group.pk |
get_fit() | get_fit |
Default method for get_fit() | get_fit.default |
Get fits from a `pk` object | get_fit.pk |
get_hessian() | get_hessian |
Default method for get_hessian() | get_hessian.default |
Get Hessian matrixes | get_hessian.pk |
get_mapping() | get_mapping |
Default method for get_mapping() | get_mapping.default |
Get mapping | get_mapping.pk |
get_nca() | get_nca |
Default method for get_nca() | get_nca.default |
Get NCA | get_nca.pk |
Get parameters for 1-compartment model | get_params_1comp |
Get parameters for 1-compartment model with clearance assumption | get_params_1comp_cl |
Get parameters for 1-compartment model with clearance assumption | get_params_1comp_fup |
Get parameters for 2-compartment model | get_params_2comp |
Get parameters to be optimized for flat model | get_params_flat |
Find the peak of a data series | get_peak |
get_prefit() | get_prefit |
Default method for get_prefit() | get_prefit.default |
Get prefit | get_prefit.pk |
get_scale_conc() | get_scale_conc |
Default method for get_scale_conc() | get_scale_conc.default |
Get scale_conc | get_scale_conc.pk |
get_scale_time() | get_scale_time |
Default method for get_scale_time() | get_scale_time.default |
Get scale_time | get_scale_time.pk |
get_settings_data_info() | get_settings_data_info |
Default method for get_settings_data_info() | get_settings_data_info.default |
Get settings_data_info | get_settings_data_info.pk |
get_settings_optimx() | get_settings_optimx |
Default method for get_settings_optimx() | get_settings_optimx.default |
Get settings_optimx | get_settings_optimx.pk |
get_settings_preprocess() | get_settings_preprocess |
Default method for get_settings_preprocess() | get_settings_preprocess.default |
Get settings_preprocess | get_settings_preprocess.pk |
Get starting values for 1-compartment model | get_starts_1comp |
Get starting values for 1-compartment model with specific clearance | get_starts_1comp_cl |
Get starting values for 1-compartment model with specific clearance | get_starts_1comp_fup |
Get starting values for 2-compartment model | get_starts_2comp |
Get starting values for flat model | get_starts_flat |
get_stat_error_model() | get_stat_error_model |
Default method for get_stat_error_model() | get_stat_error_model.default |
Get stat_error_model | get_stat_error_model.pk |
get_stat_model() | get_stat_model |
Default method for get_stat_model() | get_stat_model.default |
Get stat_model | get_stat_model.pk |
Get status | get_status |
Default method for getting status | get_status.default |
Check status of a `pk` object | get_status.pk |
Get TK stats | get_tkstats |
Default method for get_tkstats() | get_tkstats.default |
Get TK stats | get_tkstats.pk |
get_winning_model() | get_winning_model |
Default method for get_winning_model() | get_winning_model.default |
Get winning model | get_winning_model.pk |
Inverse diagonal, method 1 | hess_sd1 |
Inverse diagonal, method 2 | hess_sd2 |
Ignore unused imports | ignore_unused_imports |
Check whether an object is of class `pk` | is.pk |
Check whether an object is of class `pk_faceted` | is.pk_faceted |
Is an object class `pk_scales`? | is.pk_scales |
Is an object pkproto? | is.pkproto |
Log-likelihood | log_likelihood |
Log-likelihood | logLik.pk |
New mapping | mapping |
Log10-scaled midpoint | midpt_log10 |
1-compartment model | model_1comp |
1-compartment model that assumes non-restrictive clearance | model_1comp_cl_nonrest |
1-compartment model that assumes restrictive clearance | model_1comp_cl_rest |
1-compartment model that assumes restrictive clearance optimizes Fup | model_1comp_fup |
2-compartment model | model_2comp |
Flat model | model_flat |
nca() | nca |
Default method for nca() | nca.default |
NCA for a `pk` object | nca.pk |
Create a new `pk` object | pk |
Add a `pkproto` object to a `pk` object | pk_add |
Add pkproto object default method | pk_add.default |
Add facet_data() | pk_add.pk_facet_data |
Add a `pk_scales` object to a `pk` object. | pk_add.pk_scales |
Add a `pk_settings_data_info` object. | pk_add.pk_settings_data_info |
Add a `pk_settings_optimx` object. | pk_add.pk_settings_optimx |
Add a `pk_settings_preprocess` object. | pk_add.pk_settings_preprocess |
Add a `pk_stat_error_model` object. | pk_add.pk_stat_error_model |
Add a `pk_stat_model` object. | pk_add.pk_stat_model |
Add an `uneval` object | pk_add.uneval |
Create a new `pk_model` object | pk_model |
Subtract a `pkproto` object from a `pk` object | pk_subtract |
Subtract pkproto object default method | pk_subtract.default |
Subtract a `pk_stat_model` object. | pk_subtract.pk_stat_model |
Toxicokinetic data from the "Concentration vs. Time Database" | pkdataset_nheerlcleaned |
Plot a [pk()] object. | plot.pk |
Get predictions | predict.pk |
Print a user-friendly version of a `pk` object | print.pk |
Convert invivoPKfit output table names to the CvTdb names | rename2_cvt |
Get residuals | residuals.pk |
Root mean squared error (RMSE) | rmse |
Root mean squared error (RMSE) default method | rmse.default |
Root mean squared error | rmse.pk |
Helper function for calculating percentages of count data, by row | rowwise_calc_percentages |
rsq() | rsq |
Default method for rsq() | rsq.default |
Calculate R-squared for observed vs. predicted values | rsq.pk |
Scale concentrations | scale_conc |
Scale times | scale_time |
Data info settings | settings_data_info |
`optimx` optimizer settings | settings_optimx |
Data preprocessing settings | settings_preprocess |
Error model | stat_error_model |
Add PK model(s) to be fitted | stat_model |
Status ID for data summary info | status_data_info |
Status ID for fitting | status_fit |
Status ID for initialization | status_init |
Status ID for pre-fitting | status_prefit |
Status ID for preprocessing | status_preprocess |
Subtract various `pkproto` objects from a `pk` object | subtract_pk |
Print summary of a `pk` object | summary.pk |
Time conversion table | time_conversions |
Allowable time units | time_units |
Toxicokinetic statistics for 1-compartment model | tkstats_1comp |
Toxicokinetic statistics for 1-compartment model with specific clearance | tkstats_1comp_cl |
Toxicokinetic statistics for 1-compartment model | tkstats_2comp |
TK stats for flat model | tkstats_flat |
Transformed parameters for 2-compartment model | transformed_params_2comp |
twofold_test() | twofold_test |
Default method for twofold_test() | twofold_test.default |
Evaluate whether data and predictions are within two-fold of mean or concentration, respectively | twofold_test.pk |